ECOLOGICAL NEO-NARODNISM AND THE PEASANT ECONOMY: HISTORY AND CONTEMPORARY RELEVANCE



LV305, a dendritic cell-targeting integration-deficient ZVexTM-based lentiviral vector encoding NY-ESO-1, induces potent anti-tumor immune response

We have engineered an integration-deficient lentiviral vector, LV305, to deliver the tumor antigen NY-ESO-1 to human dendritic cells in vivo through pseudotyping with a modified Sindbis virus envelop protein.Mice immunized once with LV305 developed strong, dose-dependent, multifunctional, and cytotoxic NY-ESO-1-specific cluster of differentiation 8

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Multimorbidity in osteoarthritis and pleiotropic effects of slow-acting symptomatic drugs. Resolution of the multidisciplinary International Expert Council

In recent decades, the prevalence of osteoarthritis (OA), one of the most disabling diseases, has increased worldwide, which imposes a significant burden on society.At the international multidisciplinary Headlight Bulbs meeting, experts of various specialties (rheumatology, neurology, endocrinology, geriatrics, rehabilitation, traumatology and orth

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The Proteasome Governs Fungal Morphogenesis via Functional Connections with Hsp90 and cAMP-Protein Kinase A Signaling

ABSTRACT Protein homeostasis is critical for proliferation and viability of all organisms.For Candida albicans, protein homeostasis also modulates the transition between yeast and filamentous forms, which is critical for virulence.A key regulator of morphogenesis is the molecular chaperone Hsp90, which Curler mediates proteostasis under physiologic

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